Effects of longitudinal asymmetric distribution of a lipid core on plaque wall stress

The rupture of the atherosclerotic plaque is related to the mechanical stress and structural integrity of plaque wall tissues. In order to investigate the longitudinal asymmetry across the stenosis of the arterial plaque wall, asymmetric plaque wall models were constructed by skewing the lipid core distribution in the upstream direction. Wall stress and blood flow…

Development and characterization of viscoelastic polydimethylsiloxane phantoms for simulating arterial wall motion

Arterial wall viscoelasticity is likely to be a good diagnostic indicator of vascular disease, but only a few studies on the assessment of wall viscosity have been performed. Artery phantoms are manufactured using polydimethylsiloxane (PDMS) to simulate the viscoelastic characteristics of the artery wall, which depends on the wall tissue composition and progression of atherosclerosis.…