Effects of Cap Thickness and Lipid Core Stiffness on Atherosclerotic Plaque Wall Stress

Rupture of atherosclerotic plaque is related to mechanical stress, plaque geometry and the material properties of plaque tissues. An idea three dimensional coronary artery with eccentric stenosis was modelled, and stress analysis with fluid structure interactions was performed using ADINA in order to investigate the effects of cap thickness and lipid core stiffness on atherosclerotic…

Effects of longitudinal asymmetric distribution of a lipid core on plaque wall stress

The rupture of the atherosclerotic plaque is related to the mechanical stress and structural integrity of plaque wall tissues. In order to investigate the longitudinal asymmetry across the stenosis of the arterial plaque wall, asymmetric plaque wall models were constructed by skewing the lipid core distribution in the upstream direction. Wall stress and blood flow…

Effect of distal thickening and stiffening of plaque cap on arterial wall mechanics

To investigate the effect of longitudinal variations of cap thickness and tissue properties on wall stresses and strains along the atherosclerotic stenosis, stenotic plaque models (uniformly thick, distally thickened, homogenous, and distally stiffened) were constructed and subjected to computational stress analyses with due consideration of fluid–structure interactions (FSI). The analysis considered three different cap thicknesses—45,…

Effect of distal thickening and stiffening of plaque cap on arterial wall mechanics

To investigate the effect of longitudinal variations of cap thickness and tissue properties on wall stresses and strains along the atherosclerotic stenosis, stenotic plaque models (uniformly thick, distally thickened, homogenous, and distally stiffened) were constructed and subjected to computational stress analyses with due consideration of fluid–structure interactions (FSI). The analysis considered three different cap thicknesses—45,…